Description

1-(4-Amino-3-Bromo-5-Trifluoromethyl-Phenyl)-Ethanone is a high-purity, multi-functional aromatic ketone building block of significant commercial and research interest. Its unique molecular structure, featuring amino, bromo, and trifluoromethyl substituents, makes it a versatile intermediate for synthesizing complex molecules. This compound is primarily sought after by pharmaceutical, agrochemical, and advanced materials research and development teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its aromatic core and functional handles.
• Polymer & Dye Chemistry: Employed in the production of specialty polymers, resins, and high-performance dyes and pigments.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries for screening.

Basic Information

Product Name	1-(4-Amino-3-Bromo-5-Trifluoromethyl-Phenyl)-Ethanone
CAS No.	97760-77-5
Molecular Formula	C9H7BrF3NO
Molecular Weight	282.06 g/mol
Synonyms	1-(4-Amino-3-bromo-5-(trifluoromethyl)phenyl)ethan-1-one; 4'-Amino-3'-bromo-5'-(trifluoromethyl)acetophenone; 3-Bromo-4-amino-α,α,α-trifluoroacetophenone; 3-Bromo-4-amino-α,α,α-trifluoroacetophenone; Ethanone, 1-[4-amino-3-bromo-5-(trifluoromethyl)phenyl]-; 4-Acetyl-2-bromo-6-(trifluoromethyl)aniline
EINECS	Contact for details

Quality Control

Our 1-(4-Amino-3-Bromo-5-Trifluoromethyl-Phenyl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and consistent quality suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.