Description

2-Fluoro-D-Phenylalanine is a non-natural, fluorinated amino acid derivative of significant interest in advanced pharmaceutical and biochemical research. Its core value lies in the strategic incorporation of fluorine, which can dramatically alter the metabolic stability, bioavailability, and binding affinity of peptide-based therapeutics. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel peptide drugs, enzyme inhibitors, and as a building block in Positron Emission Tomography (PET) tracer synthesis.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of fluorinated peptide drugs and protease inhibitors.
• PET Radiopharmaceutical Precursor: Used in the development of F-18 labeled tracers for diagnostic imaging in oncology and neurology.
• Biochemical Research: Employed in enzyme studies and metabolic pathway analysis to investigate the effects of fluorination on protein structure and function.
• Agrochemical Research: Serves as a specialty intermediate in the development of novel, fluorinated bioactive compounds.
• Chiral Catalyst & Ligand Synthesis: Utilized for creating sophisticated chiral auxiliaries and ligands for asymmetric synthesis.

Basic Information

Product Name	2-Fluoro-D-Phenylalanine
CAS No.	97731-02-7
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	(R)-2-Amino-3-(2-fluorophenyl)propanoic acid; D-2-Fluorophenylalanine; (R)-2-Fluorophenylalanine; D-α-Amino-2-fluorohydrocinnamic acid; F-D-Phe-OH; 2-F-D-Phe; D-Phe(2-F)
EINECS	Contact for details

Quality Control

Our 2-Fluoro-D-Phenylalanine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (D-Isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.