Description

Mitoxantrone Dicarboxylic Acid is a key pharmaceutical intermediate and a derivative of the anthracenedione class. This compound is of significant commercial importance for its role in the synthesis of active pharmaceutical ingredients (APIs) and advanced research applications. It is primarily required by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of the chemotherapeutic agent Mitoxantrone Hydrochloride and related analogs.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in research and development for new anthracenedione-based drugs.
• Biochemical Research: Used in studies investigating DNA intercalation mechanisms and topoisomerase II inhibition.
• Reference Standard: Employed as a high-purity standard in analytical laboratories for quality control and method validation.
• Fine Chemical Synthesis: Utilized in custom synthesis and process development for specialized chemical entities.

Basic Information

Product Name	Mitoxantrone Dicarboxylic Acid
CAS No.	97729-57-2
Molecular Formula	C22H28N4O6
Molecular Weight	444.48 g/mol
Synonyms	1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione dicarboxylic acid; Mitoxantrone Diacid; Mitoxantrone Dicarboxylate; DHAQ Dicarboxylic Acid; 1,4-Dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthra-9,10-quinone-2,3-dicarboxylic Acid; CL 232,315 Dicarboxylic Acid; Novantrone Dicarboxylic Acid
EINECS	Contact for details

Quality Control

Our Mitoxantrone Dicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting full specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; appropriate handling procedures should be followed to maintain stability and purity.

Specification

Item	Specification
Appearance	Blue to dark blue solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.