Description

(3S)-3Aβ,4,5,5A,6,7,8,9,9Aβ,9Bα-Decahydro-5α,9Aβ-Dihydroxy-3β,5Aα-Dimethyl-9-Methylenenaphtho[1,2-B]Furan-2(3H)-One is a complex, high-purity sesquiterpene lactone derivative with a unique steroidal-like fused ring structure. This compound is valued as a critical advanced pharmaceutical intermediate and a versatile scaffold for synthetic organic chemistry, enabling the development of novel bioactive molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of potential therapeutic agents, particularly in steroid-mimetic drug discovery.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Agrochemical Synthesis: Acts as a precursor for developing novel plant growth regulators or bioactive agents with specific modes of action.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic & R&D: Utilized in university and corporate laboratories for methodological studies in organic synthesis, including cyclization and functionalization reactions.
• Biochemical Probe Development: Potential use in creating molecular probes to study biological pathways and enzyme interactions.

Basic Information

Item	Detail
Product Name	(3S)-3Aβ,4,5,5A,6,7,8,9,9Aβ,9Bα-Decahydro-5α,9Aβ-Dihydroxy-3β,5Aα-Dimethyl-9-Methylenenaphtho[1,2-B]Furan-2(3H)-One
CAS No.	97649-06-4
Molecular Formula	C17H24O4
Molecular Weight	292.37 g/mol
Synonyms	9-Methylenenaphtho[1,2-b]furan-2(3H)-one, 3aβ,4,5,5a,6,7,8,9,9aβ,9bα-decahydro-5α,9aβ-dihydroxy-3β,5aα-dimethyl-, (3S)-; (3S)-3aβ,4,5,5a,6,7,8,9,9aβ,9bα-Decahydro-5α,9aβ-dihydroxy-3β,5aα-dimethyl-9-methylenenaphtho[1,2-b]furan-2(3H)-one; Sesquiterpene lactone derivative; 97649-06-4; 5α,9aβ-Dihydroxy-3β,5aα-dimethyl-9-methylenenaphtho[1,2-b]furan-2(3H)-one
EINECS	Contact for details

Quality Control

Our (3S)-3Aβ,4,5,5A,6,7,8,9,9Aβ,9Bα-Decahydro-5α,9Aβ-Dihydroxy-3β,5Aα-Dimethyl-9-Methylenenaphtho[1,2-B]Furan-2(3H)-One is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.