Description

Piperazine, 1-((3,5-Bis(Trifluoromethyl)Phenyl)Sulfonyl)-, Monohydroch Loride is a specialized sulfonamide derivative of piperazine, featuring a highly electron-withdrawing bis(trifluoromethyl)phenyl group. This compound is valued for its role as a key synthetic intermediate and building block in advanced organic synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecules with specific biological activities.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, metabolic diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging the physicochemical properties imparted by the trifluoromethyl groups.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new chemical reactions, catalysis, and material science applications.
• Ligand & Catalyst Preparation: Acts as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	Piperazine, 1-((3,5-Bis(Trifluoromethyl)Phenyl)Sulfonyl)-, Monohydroch Loride
CAS No.	97630-12-1
Molecular Formula	C13H13ClF6N2O2S
Molecular Weight	410.76 g/mol
Synonyms	1-[(3,5-Bis(trifluoromethyl)phenyl)sulfonyl]piperazine hydrochloride; N-[(3,5-Bis(trifluoromethyl)phenyl)sulfonyl]piperazine monohydrochloride; 3,5-Bis(trifluoromethyl)benzenesulfonamide, N-(piperazinyl)-, monohydrochloride; Piperazine, 1-[(3,5-bis(trifluoromethyl)phenyl)sulfonyl]-, hydrochloride (1:1); 97630-12-1; 1-(3,5-Bis(trifluoromethyl)phenylsulfonyl)piperazine HCl
EINECS	Contact for details

Quality Control

Our Piperazine, 1-((3,5-Bis(Trifluoromethyl)Phenyl)Sulfonyl)-, Monohydroch Loride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from strong acids, strong bases, and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.