Description

2,4(1H,3H)-Pyrimidinedione, 1-(3,5-Di-o-Benzoyl-2-Deoxy-2-Fluoro-β-D-Arabinofuranosyl)-5-Methyl- is a high-purity, fluorinated nucleoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate or active pharmaceutical ingredient (API) precursor in the creation of novel antiviral and anticancer therapeutics. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and API manufacturers focused on nucleoside analogue drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of antiviral and anticancer nucleoside analogues.
• Antiviral Drug Research: Used in the development of potential therapeutics targeting viral polymerases.
• Oncology Research: Investigated as a precursor for chemotherapeutic agents that interfere with DNA synthesis in cancer cells.
• Biochemical Tool: Employed in enzymatic studies and as a substrate analog to understand nucleic acid metabolism.
• Process Chemistry: Serves as a starting material for scale-up and optimization of API manufacturing processes under GMP conditions.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	2,4(1H,3H)-Pyrimidinedione, 1-(3,5-Di-o-Benzoyl-2-Deoxy-2-Fluoro-β-D-Arabinofuranosyl)-5-Methyl-
CAS No.	97614-47-6
Molecular Formula	C24H21FN2O7
Molecular Weight	468.43 g/mol
Synonyms	5-Methyl-1-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)uracil; 2'-Deoxy-2'-fluoro-5-methyl-β-D-arabinofuranosyluracil 3',5'-Dibenzoate; 1-(3,5-Di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyluracil; 2'-Fluoro-2'-deoxy-5-methyl-β-D-arabinofuranosyluracil 3',5'-dibenzoate; FMAU 3',5'-Dibenzoate; 1-(3,5-Di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We offer material suitable for research and development under a quality management system. Certificates of Analysis (COA) providing detailed results for identity, purity, and impurity profiles are available upon request. Specifications can be aligned with customer requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.