Description

3',5'-Di-o-Benzoyl Fialuridine is a key nucleoside derivative and a protected intermediate of significant interest in pharmaceutical research and development. This compound is crucial for the synthesis of modified nucleosides, enabling precise chemical modifications that are essential for creating novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral drug discovery, particularly for targeting viral polymerases, and in the development of prodrugs and diagnostic probes.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Research: Used in the development and study of potential therapeutics for viral infections, including hepatitis and herpes viruses.
• Prodrug Synthesis: Serves as a protected precursor for creating prodrugs with enhanced bioavailability and targeted delivery.
• Biochemical Tool: Employed in biochemical assays to study enzyme kinetics and inhibition, particularly of viral polymerases.
• Organic Synthesis: Utilized in academic and industrial laboratories for complex organic transformations involving sensitive nucleoside chemistry.
• Diagnostic Agent Development: Acts as a starting material for synthesizing labeled compounds used in molecular diagnostics and imaging.

Basic Information

Product Name	3',5'-Di-o-Benzoyl Fialuridine
CAS No.	97614-45-4
Molecular Formula	C24H21FN2O7
Molecular Weight	468.44 g/mol
Synonyms	1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil 3',5'-Dibenzoate; FIAU 3',5'-Dibenzoate; 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil Di-O-benzoate; 2'-Fluoro-5-iodo-arac; 2'-F-5-I-arac Dibenzoate; 5-Iodo-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)uracil 3',5'-Dibenzoate; FIAC Dibenzoate Derivative
EINECS	Contact for details

Quality Control

Our 3',5'-Di-o-Benzoyl Fialuridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.