Description

Flb 131, S-(-)-3-Chloro-5-Ethyl-n-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-6-Hydroxy-2-Methoxybenzamide Hydrochloride is a high-purity, chiral benzamide derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmacological reference standard and a key synthetic intermediate for the creation of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in neuroscience and receptor-targeted drug discovery programs.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in drug substance and product testing.
• Neuroscience Research: Acts as a crucial intermediate or ligand in the study of specific neurological receptors and pathways.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key chiral building block in the multi-step synthesis of potential drug candidates.
• Preclinical Studies: Employed in pharmacological and toxicological profiling during early-stage drug discovery.
• Process Chemistry Development: Used to optimize synthetic routes and scale-up parameters for potential manufacturing.
• Academic Research: Utilized in university laboratories for medicinal chemistry projects and pharmacological investigations.

Basic Information

Product Name	Flb 131, S-(-)-3-Chloro-5-Ethyl-n-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-6-Hydroxy-2-Methoxybenzamide Hydrochloride
CAS No.	97612-24-3
Molecular Formula	C20H30ClN2O3 • HCl
Molecular Weight	419.38 g/mol (for hydrochloride salt)
Synonyms	FLB 131; (-)-FLB 131; S-(-)-FLB 131; (S)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride; S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide monohydrochloride; FLB-131 HCl; (S)-FLB 131 hydrochloride
EINECS	Contact for details

Quality Control

Our Flb 131 is manufactured under controlled conditions to ensure high chemical and chiral purity, meeting the stringent requirements of research and development. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, IR, MS). A detailed Certificate of Analysis (COA) is provided, documenting all critical quality attributes. We support compliance with cGMP standards for advanced intermediates used in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (S-enantiomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.