Description

[3R,6Aα,10Bα,(-)]-Dodecahydro-3,4Aβ,7,7,10Aβ-Pentamethyl-1H-Naphtho[2,1-B]Pyran-3α-Acetaldehyde is a high-purity, complex sesquiterpenoid derivative with a defined stereochemistry, making it a valuable chiral building block and intermediate in advanced organic synthesis. Its intricate fused-ring structure is critical for imparting specific biological activity and olfactory properties in final formulations. This compound is essential for R&D and production teams in the fragrance, flavor, and pharmaceutical industries seeking to develop novel, high-value products with precise molecular characteristics.

Application

• Fragrance & Flavor Intermediate: Serves as a key precursor in the synthesis of sophisticated amber, woody, and musk odorants for premium perfumery and flavoring agents.
• Pharmaceutical Research: Used as a chiral scaffold or intermediate in the development of novel therapeutic agents, particularly in medicinal chemistry programs targeting complex natural product analogs.
• Fine Chemical Synthesis: Acts as a specialized building block for synthesizing other complex sesquiterpenoids and sterically hindered molecules in custom synthesis and process development.
• Academic & Industrial R&D: Employed in chemical research to study structure-activity relationships (SAR), catalysis, and novel synthetic pathways due to its defined stereocenters.
• High-End Cosmetic Ingredients: Potential use in the synthesis of active ingredients or specialty additives for cosmetic formulations requiring specific isomeric purity.

Basic Information

Item	Details
Product Name	[3R,6Aα,10Bα,(-)]-Dodecahydro-3,4Aβ,7,7,10Aβ-Pentamethyl-1H-Naphtho[2,1-B]Pyran-3α-Acetaldehyde
CAS No.	97549-56-9
Molecular Formula	C20H34O2
Molecular Weight	306.48 g/mol
Synonyms	(-)-Ambrox; (3R,6Aα,10Bα)-Dodecahydro-3,4Aβ,7,7,10Aβ-pentamethyl-1H-naphtho[2,1-b]pyran-3α-acetaldehyde; 3α-Acetaldehyde-1H-naphtho[2,1-b]pyran derivative; Ambroxide related compound; Sesquiterpenoid aldehyde; Chiral naphthopyran derivative
EINECS	Contact for details

Quality Control

Our [3R,6Aα,10Bα,(-)]-Dodecahydro-3,4Aβ,7,7,10Aβ-Pentamethyl-1H-Naphtho[2,1-B]Pyran-3α-Acetaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high isomeric and chemical purity consistent with research and industrial-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, the product should be stored under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.