Description

[11As,(-)]-2,3,4,10,11,11Aα-Hexahydro-1,1-Dimethyl-8-(1-Methylethyl)-1H-Dibenzo[A,D]Cycloheptene-7-Ol CAS NO 97403-22-0 is a high-purity, stereochemically defined organic compound belonging to the dibenzocycloheptene class. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in sophisticated organic synthesis. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of novel therapeutic agents and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Asymmetric Synthesis: Employed as a chiral precursor or ligand in catalytic asymmetric reactions to induce stereoselectivity.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Organic Synthesis Building Block: Utilized for constructing complex polycyclic frameworks in natural product synthesis and material science.

Basic Information

Product Name	[11As,(-)]-2,3,4,10,11,11Aα-Hexahydro-1,1-Dimethyl-8-(1-Methylethyl)-1H-Dibenzo[A,D]Cycloheptene-7-Ol
CAS No.	97403-22-0
Molecular Formula	C21H28O
Molecular Weight	296.45 g/mol
Synonyms	(-)-11aS-Hexahydro-1,1-dimethyl-8-(1-methylethyl)-1H-dibenzo[a,d]cyclohepten-7-ol; (11aS)-1,1-Dimethyl-8-(propan-2-yl)-2,3,4,10,11,11a-hexahydro-1H-dibenzo[a,d]cyclohepten-7-ol; Levocetirizine Impurity; Levocetirizine Related Compound A; Cetirizine Impurity; Dibenzocycloheptenol derivative; Chiral dibenzocycloheptene intermediate.
EINECS	Contact for details

Quality Control

Our [11As,(-)]-2,3,4,10,11,11Aα-Hexahydro-1,1-Dimethyl-8-(1-Methylethyl)-1H-Dibenzo[A,D]Cycloheptene-7-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral assay, to ensure it meets stringent specifications for use in pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.