Description

Proline, 3,5-Dimethyl-, Methyl Ester, (2-α-,3-Ba-,5-α-)- (9Ci) is a specialized proline derivative, a key chiral building block in advanced organic synthesis. Its value lies in providing a sterically defined, functionalized pyrrolidine scaffold essential for constructing complex molecules with high stereochemical fidelity. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, asymmetric synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new drug candidates, particularly for protease inhibitors and other biologically active molecules.
• Asymmetric Catalysis Ligand Precursor: Used in the synthesis of novel chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Synthesis: Employed as a building block in the development of advanced pesticides and herbicides with specific stereochemical requirements.
• Peptidomimetics Research: Integral for creating conformationally constrained peptide analogs to study protein-protein interactions and develop therapeutic agents.
• Fine Chemical Production: Utilized in the custom synthesis of high-value, specialty chemicals for research and small-scale commercial applications.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and exploring new chemical space in discovery chemistry.

Basic Information

Product Name	Proline, 3,5-Dimethyl-, Methyl Ester, (2-α-,3-Ba-,5-α-)- (9Ci)
CAS No.	97373-42-7
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	Methyl (2S,3R,5S)-3,5-dimethylpyrrolidine-2-carboxylate; (2S,3R,5S)-3,5-Dimethylproline methyl ester; L-Proline, 3,5-dimethyl-, methyl ester, (2-alpha,3-beta,5-alpha)-; 3,5-Dimethyl-L-proline methyl ester; Methyl 3,5-dimethylprolinate; (2S,3R,5S)-Methyl 3,5-dimethylpyrrolidine-2-carboxylate; Proline derivative 97373-42-7
EINECS	Contact for details

Quality Control

Our Proline, 3,5-Dimethyl-, Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is supplied with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.