Description

[4S,(-)]-3,4,4Aβ,7,8,8Aβ-Hexahydro-6-Methyl-4β-(1-Methylethyl)-1-Naphthalenecarboxylic Acid is a high-purity, stereochemically defined intermediate of significant interest in advanced organic synthesis. Its value lies in its complex, polycyclic structure which serves as a versatile chiral building block for the development of novel active compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating new therapeutic agents and crop protection products with specific stereochemical requirements.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in therapeutic areas requiring complex, polycyclic molecular architectures.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents, where its specific stereochemistry can be critical for biological activity and environmental selectivity.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in academic and industrial research focused on developing new stereoselective synthetic methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of other high-value, specialty chemicals where its decalin-based core structure is a required component.
• Material Science Research: Potential building block for the synthesis of novel organic materials with specific chiral or structural properties.

Basic Information

Product Name	[4S,(-)]-3,4,4Aβ,7,8,8Aβ-Hexahydro-6-Methyl-4β-(1-Methylethyl)-1-Naphthalenecarboxylic Acid
CAS No.	97286-73-2
Molecular Formula	C₁₆H₂₄O₂
Molecular Weight	248.36 g/mol
Synonyms	(4S)-3,4,4a,7,8,8a-Hexahydro-6-methyl-4-(1-methylethyl)-1-naphthalenecarboxylic acid; (-)-3,4,4aβ,7,8,8aβ-Hexahydro-6-methyl-4β-isopropyl-1-naphthoic acid; (4S)-4-Isopropyl-6-methyl-1,2,3,4,4a,7,8,8a-octahydronaphthalene-1-carboxylic acid; 4β-Isopropyl-6-methyl-1,2,3,4,4aβ,7,8,8aβ-octahydro-1-naphthoic acid; (4S,4aR,8aS)-4-Isopropyl-6-methyl-1,2,3,4,4a,7,8,8a-octahydronaphthalene-1-carboxylic acid; Chiral Decalin Carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our [4S,(-)]-3,4,4Aβ,7,8,8Aβ-Hexahydro-6-Methyl-4β-(1-Methylethyl)-1-Naphthalenecarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.