Description

H-Ile-His-Oh is a high-purity dipeptide derivative consisting of isoleucine and histidine residues. This compound is a critical building block in advanced pharmaceutical research and peptide synthesis, offering precise structural control for developing novel therapeutic agents. It is primarily utilized by R&D scientists and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications ranging from drug discovery to the production of complex peptide-based APIs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs) and novel drug candidates.
• Biochemical Research: Used as a standard or reagent in proteomics, enzymology, and metabolic pathway studies to investigate biological functions.
• Peptide Synthesis: An essential building block in solid-phase and solution-phase peptide synthesis (SPPS) for constructing custom peptide sequences.
• Nutraceutical Development: Investigated for potential use in the formulation of specialized bioactive peptides for dietary supplements.
• Cosmetic Peptides: Explored as a component in the development of anti-aging or skin-conditioning cosmetic peptides.

Basic Information

Item	Detail
Product Name	H-Ile-His-Oh
CAS No.	97284-12-3
Molecular Formula	C15H22N4O4
Molecular Weight	322.36 g/mol
Synonyms	Isoleucyl-histidine; L-Isoleucyl-L-histidine; Ile-His; H-Ile-His-OH; L-Ile-L-His; N-(2-Amino-3-methylpentanoyl)-L-histidine; (2S)-2-[[(2S)-2-Amino-3-methylpentanoyl]amino]-3-(1H-imidazol-4-yl)propanoic acid
EINECS	Contact for details

Quality Control

Our H-Ile-His-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and MS. Certificates of Analysis (COA) documenting all critical parameters are available upon request to ensure full traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D: Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.