Description

n-Boc-n-Methyl-3-Cyclohexanyl-L-Alanine is a protected, non-natural amino acid derivative featuring a cyclohexyl side chain and a tert-butoxycarbonyl (Boc) protecting group on the secondary amine. This compound is a critical chiral building block in the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis companies for developing novel therapeutic agents, including protease inhibitors and other bioactive molecules.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptidomimetic Synthesis: Used to incorporate constrained, cycloaliphatic structures into peptide backbones to enhance metabolic stability and bioavailability.
• Protease Inhibitor Development: Serves as a core building block for creating inhibitors targeting specific enzymes like HCV protease or renin.
• Chemical Biology & Drug Discovery: Employed in the synthesis of specialized amino acids for structure-activity relationship (SAR) studies and library generation.
• Fine Chemical Synthesis: Used in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.

Basic Information

Product Name	n-Boc-n-Methyl-3-Cyclohexanyl-L-Alanine
CAS No.	97269-22-2
Molecular Formula	C₁₅H₂₇NO₄
Molecular Weight	285.38 g/mol
Synonyms	(2S)-2-[[(1,1-Dimethylethoxy)carbonyl](methyl)amino]-3-(3-cyclohexen-1-yl)propanoic Acid; (S)-3-(3-Cyclohexen-1-yl)-2-[(tert-butoxycarbonyl)(methyl)amino]propanoic Acid; Boc-N-Me-3-cyclohexenyl-L-alanine; tert-Butyl (S)-(1-((3-cyclohexen-1-yl)methylcarbamoyl)ethyl)carbamate; N-Boc-N-methyl-3-cyclohexenyl-L-alanine; N-tert-Butoxycarbonyl-N-methyl-3-cyclohexenyl-L-alanine
EINECS	Contact for details

Quality Control

Our n-Boc-n-Methyl-3-Cyclohexanyl-L-Alanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.