Description

2-Methylcrotonic Acid (3Ar,4R,7R,9S,10Z,11Ar)-2,3,3A,4,5,6,7,8,9,11A-Decahydro-7,9-Dihydroxy-10-Methyl-3,6-Bis(Methylene)-2-Oxocyclodeca[B]Furan-4-Yl Ester is a complex, high-purity organic ester with a defined stereochemistry, serving as a critical advanced pharmaceutical intermediate and a valuable building block in sophisticated organic synthesis. Its precise molecular architecture makes it indispensable for research and development in creating novel active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is primarily targeted at pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and manufacturers of high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of complex drug candidates, particularly in oncology and anti-infective therapeutic areas.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex natural product analogs and novel molecular scaffolds.
• Process Chemistry Development: Serves as a reference standard or starting material for developing scalable synthetic routes for new chemical entities.
• Fine Chemical Production: Intermediate in the manufacture of specialty agrochemicals, flavors, and fragrances requiring high stereochemical purity.
• Biochemical Research: Potential use as a probe or substrate in enzymatic studies due to its specific stereocenters and functional groups.

Basic Information

Product Name	2-Methylcrotonic Acid (3Ar,4R,7R,9S,10Z,11Ar)-2,3,3A,4,5,6,7,8,9,11A-Decahydro-7,9-Dihydroxy-10-Methyl-3,6-Bis(Methylene)-2-Oxocyclodeca[B]Furan-4-Yl Ester
CAS No.	97233-10-8
Molecular Formula	C20H26O6
Molecular Weight	362.42 g/mol
Synonyms	(3aR,4R,7R,9S,10Z,11aR)-2,3,3a,4,5,6,7,8,9,11a-Decahydro-7,9-dihydroxy-10-methyl-3,6-bis(methylene)-2-oxocyclodeca[b]furan-4-yl 2-methylbut-2-enoate; 2-Methylcrotonic Acid Ester of a Decahydrofurano[3,4-b]furan Derivative; Tiglic Acid (3aR,4R,7R,9S,10Z,11aR)-2,3,3a,4,5,6,7,8,9,11a-decahydro-7,9-dihydroxy-10-methyl-3,6-bis(methylene)-2-oxocyclodeca[b]furan-4-yl Ester; CAS 97233-10-8.
EINECS	Contact for details

Quality Control

Our 2-Methylcrotonic Acid ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, chiral purity determination, and structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support development and commercial projects requiring adherence to cGMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.