Description

Mono-2-o-(p-Toluenesulfonyl)-γ-Cyclodextrin is a selectively modified derivative of γ-cyclodextrin, featuring a single tosyl group at the 2-O position, which serves as a crucial intermediate for further functionalization. This compound matters because it provides a defined, reactive handle for synthesizing advanced drug delivery systems, molecular sensors, and separation materials with tailored properties. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for developing novel host-guest complexes and chiral separation media.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing targeted drug delivery carriers and prodrugs.
• Chiral Separation Agent: Used in the development of stationary phases for HPLC to resolve enantiomers.
• Molecular Encapsulation Studies: Serves as a model compound in supramolecular chemistry research for studying guest-host interactions.
• Sensor Development: Acts as a precursor for creating fluorescent or electrochemical molecular sensors.
• Polymer Modification: Reactive site for grafting cyclodextrin units onto polymers to create functional materials.
• Catalyst Support: Used to anchor catalytic species for applications in asymmetric synthesis.

Basic Information

Item	Details
Product Name	Mono-2-o-(p-Toluenesulfonyl)-γ-Cyclodextrin
CAS No.	97227-32-2
Molecular Formula	C55H84O42S
Molecular Weight	1417.29 g/mol
Synonyms	Mono-2-O-tosyl-γ-cyclodextrin; 2-O-(p-Toluenesulfonyl)-γ-cyclodextrin; 2-O-Tosylated Gamma Cyclodextrin; γ-CD-2-OTs; 6^A-O-Mono-p-toluenesulfonyl-γ-cyclodextrin; Heptakis[6-O-(p-toluenesulfonyl)]-γ-cyclodextrin (related); Ts-γ-CD; 2-O-(4-Methylbenzenesulfonyl)-γ-cyclodextrin
EINECS	Contact for details

Quality Control

Our Mono-2-o-(p-Toluenesulfonyl)-γ-Cyclodextrin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. Avoid prolonged exposure to high humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.