Description

n-[2-Chloro-4-(2-Pyrrolidin-1-Ylpropanoyl)Phenyl]Acetamide Hydrochloride is a high-purity, non-racemic chiral compound used as a critical intermediate in advanced pharmaceutical synthesis. Its value lies in its role as a sophisticated building block for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. This product is essential for research institutions and pharmaceutical manufacturers engaged in the development of new drugs, agrochemicals, and other fine chemicals where precise stereochemistry and functional group compatibility are paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the production of advanced, high-efficacy pesticides and herbicides that require specific stereoisomers for optimal activity.
• Chemical Research: Serves as a valuable reference standard and starting material in academic and industrial laboratories for methodological studies in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of complex specialty chemicals where the pyrrolidine and acetamide functionalities are required.
• Process Chemistry Development: Utilized for scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	n-[2-Chloro-4-(2-Pyrrolidin-1-Ylpropanoyl)Phenyl]Acetamide Hydrochloride
CAS No.	97111-05-2
Molecular Formula	C₁₅H₂₀ClN₂O₂·HCl
Molecular Weight	333.25 g/mol
Synonyms	2-Chloro-4-(2-(1-pyrrolidinyl)propanoyl)acetanilide hydrochloride; 1-[2-Chloro-4-(acetylamino)phenyl]-2-(1-pyrrolidinyl)-1-propanone hydrochloride; N-[2-Chloro-4-[2-(pyrrolidin-1-yl)propanoyl]phenyl]acetamide hydrochloride; Acetamide, N-[2-chloro-4-[2-(1-pyrrolidinyl)-1-oxopropyl]phenyl]-, hydrochloride; (R/S)-N-[2-Chloro-4-(2-pyrrolidin-1-ylpropanoyl)phenyl]acetamide hydrochloride
EINECS	Contact for details

Quality Control

Our n-[2-Chloro-4-(2-Pyrrolidin-1-Ylpropanoyl)Phenyl]Acetamide Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (specify enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.