Description

4-Thiazolecarboxylicacid,2-(1-Aminoethyl)-,Ethylester,(R)-(9Ci) is a chiral, non-proteinogenic amino acid derivative featuring a thiazole heterocycle. This compound is a valuable synthetic intermediate and building block in advanced organic synthesis, particularly for the construction of complex molecules with biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Serves as a building block for creating novel pesticides, herbicides, and fungicides with specific stereochemical requirements.
• Peptidomimetics & Bioactive Molecule Design: Used to incorporate the thiazole moiety into peptide backbones or other scaffolds to enhance stability, bioavailability, or biological activity.
• Ligand & Catalyst Development: Employed in the synthesis of chiral ligands for asymmetric catalysis or as a precursor for metal-chelating agents.
• Chemical Research & Process Development: Utilized in academic and industrial R&D for methodological studies and scale-up process optimization.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in related chemical production.

Basic Information

Product Name	4-Thiazolecarboxylicacid,2-(1-Aminoethyl)-,Ethylester,(R)-(9Ci)
CAS No.	96965-18-3
Molecular Formula	C8H12N2O2S
Molecular Weight	200.26 g/mol
Synonyms	(R)-2-(1-Aminoethyl)-4-thiazolecarboxylic acid ethyl ester; Ethyl (2R)-2-(1-aminoethyl)-1,3-thiazole-4-carboxylate; (R)-Ethyl 2-(1-aminoethyl)thiazole-4-carboxylate; 2-[(1R)-1-Aminoethyl]-1,3-thiazole-4-carboxylic Acid Ethyl Ester; 4-Thiazolecarboxylic acid, 2-(1-aminoethyl)-, ethyl ester, (R)-; (R)-ATET; 96965-18-3
EINECS	Contact for details

Quality Control

Our production of 4-Thiazolecarboxylicacid,2-(1-Aminoethyl)-,Ethylester,(R)-(9Ci) adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as chiral purity, chemical assay, and impurity profiles. Our quality management system supports the needs of cGMP-compliant applications for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.