Description

Trt-D-Cys(Trt)-Oh·Dea CAS NO 96909-04-5 is a protected derivative of D-cysteine, a non-natural amino acid enantiomer, complexed with diethylamine. This compound is a critical building block in the synthesis of complex peptides and peptidomimetics, where the orthogonal protection of the thiol group is essential. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced peptide chemistry, chiral synthesis, and the development of therapeutic agents and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key chiral intermediate for incorporating D-cysteine residues into peptide chains with thiol protection intact.
• Pharmaceutical Research: For the development of peptide-based drugs, enzyme inhibitors, and receptor ligands that require specific stereochemistry and protected functional groups.
• Bioconjugation Chemistry: Serving as a precursor for creating site-specific protein modifications, antibody-drug conjugates (ADCs), and labeled biomolecules.
• Chemical Biology: Used in the synthesis of custom peptides for studying protein-protein interactions, enzyme mechanisms, and cellular signaling pathways.
• Process Development: Employed in the scale-up and optimization of synthetic routes for novel active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Trt-D-Cys(Trt)-Oh·Dea
CAS No.	96909-04-5
Molecular Formula	C31H33NO2S · C4H11N
Molecular Weight	Contact for details
Synonyms	D-Cysteine, N-[(phenylmethyl)thio]-, S-(triphenylmethyl)-, compd. with N-ethylethanamine (1:1); Fmoc-D-Cys(Trt)-OH·DCHA; D-Cysteine, S-trityl-, N-Fmoc derivative; N-α-Fmoc-S-trityl-D-cysteine; N-Fluorenylmethoxycarbonyl-S-trityl-D-cysteine; Fmoc-D-Cys(Trt)-OH diethylamine salt; Protected D-cysteine derivative; Trt-D-Cysteine(Trt)-OH DEA salt
EINECS	Contact for details

Quality Control

Our Trt-D-Cys(Trt)-Oh·Dea is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and peptide synthesis. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep container tightly sealed in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.