Description

(R)-(-)-(2,2-Dimethyl-[1,3]-Dioxolan-4-Yl)-Methylamine is a high-value chiral amine building block featuring a protected diol moiety. This compound is essential for the stereoselective synthesis of complex molecules, offering a critical handle for introducing chirality and functional diversity. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key precursor for the production of enantiomerically pure drugs, particularly in antiviral, cardiovascular, and central nervous system (CNS) therapeutic areas.
• Asymmetric Catalyst Ligand Synthesis: Used to construct sophisticated ligand frameworks for transition metal catalysts employed in enantioselective transformations.
• Natural Product and Alkaloid Synthesis: Serves as a versatile chiral synthon in the total synthesis of complex natural products and bioactive alkaloids.
• Agrochemical Intermediate: Employed in the research and development of chiral pesticides and herbicides where specific stereochemistry is required for bioactivity.
• Advanced Material Precursor: Utilized in the synthesis of chiral monomers or additives for specialty polymers and functional materials.

Basic Information

Product Name	(R)-(-)-(2,2-Dimethyl-[1,3]-Dioxolan-4-Yl)-Methylamine
CAS No.	96894-67-6
Molecular Formula	C6H13NO2
Molecular Weight	131.17 g/mol
Synonyms	(R)-(-)-2-Amino-2,2-dimethyldioxolane-4-methanol; (R)-4-(Aminomethyl)-2,2-dimethyl-1,3-dioxolane; (R)-2,2-Dimethyl-1,3-dioxolane-4-methanamine; (R)-(-)-1,3-Dioxolane-4-methanamine, 2,2-dimethyl-; (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methylamine; (R)-(-)-4-Aminomethyl-2,2-dimethyl-1,3-dioxolane; (R)-(-)-Dioxolane Methylamine Derivative
EINECS	Contact for details

Quality Control

Our (R)-(-)-(2,2-Dimethyl-[1,3]-Dioxolan-4-Yl)-Methylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.