Description

(E)-5-[(1S,8Aβ)-Decahydro-1,2α,4Aα-Trimethyl-5-Methylenenaphthalen-1β-Yl]-3-Formyl-3-Pentenoic Acid CAS NO 96888-27-6 is a high-purity, advanced pharmaceutical intermediate characterized by its complex diterpenoid structure. This compound matters as a critical building block in the synthesis of novel therapeutic agents, offering researchers a reliable and well-defined starting material for complex organic transformations. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors focused on developing new drug candidates.

Application

This specialized intermediate serves as a key precursor in several high-value chemical synthesis pathways. Its primary applications include:

• Pharmaceutical Intermediate: Core building block for the synthesis of novel diterpenoid-based drug candidates and active pharmaceutical ingredients (APIs).
• Organic Synthesis Research: Used in academic and industrial R&D for studying complex cyclization reactions and stereoselective transformations.
• Medicinal Chemistry: A valuable scaffold for constructing compound libraries aimed at biological target screening and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Serves as a reference standard and starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	(E)-5-[(1S,8Aβ)-Decahydro-1,2α,4Aα-Trimethyl-5-Methylenenaphthalen-1β-Yl]-3-Formyl-3-Pentenoic Acid
CAS No.	96888-27-6
Molecular Formula	C20H30O3
Molecular Weight	318.45 g/mol
Synonyms	(E)-5-[(1S,8aβ)-Decahydro-1,2α,4aα-trimethyl-5-methylenenaphthalen-1β-yl]-3-formyl-3-pentenoic acid; 3-Formyl-3-pentenoic acid derivative; Abietic acid derivative intermediate; Diterpenoid aldehyde acid; 5-(Decahydro-1,2α,4aα-trimethyl-5-methylenenaphthalen-1β-yl)-3-formyl-3-pentenoic acid; (1S,4aR,8aR)-5-(5-Formyl-3-pentenyl)-1,4a-dimethyl-6-methylenedecahydronaphthalene-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our (E)-5-[(1S,8Aβ)-Decahydro-1,2α,4Aα-Trimethyl-5-Methylenenaphthalen-1β-Yl]-3-Formyl-3-Pentenoic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.