Description

(S)-(+)-2-(p-Toluenesulfonate)-1,2-Propanediol CAS NO 96882-98-3 is a high-purity chiral building block and pharmaceutical intermediate, specifically the (S)-enantiomer of a tosylated diol. This compound is valued for its role in asymmetric synthesis, where it serves as a key precursor for introducing chirality into target molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system (CNS) drug candidates.
• Asymmetric Synthesis: Used as a starting material or resolving agent in stereoselective reactions to construct complex molecules with defined three-dimensional structures.
• Agrochemical Research: Employed in the development of chiral pesticides and herbicides where specific stereochemistry is required for biological activity and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in homogeneous catalysis.
• Fine Chemical Production: Integral in the manufacture of specialty chemicals, flavors, and fragrances that require high enantiomeric purity.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research within university and corporate laboratories.

Basic Information

Item	Details
Product Name	(S)-(+)-2-(p-Toluenesulfonate)-1,2-Propanediol
CAS No.	96882-98-3
Molecular Formula	C10H14O4S
Molecular Weight	230.28 g/mol
Synonyms	(S)-(+)-1,2-Propanediol 2-(4-Methylbenzenesulfonate); (S)-2-O-Tosyl-1,2-propanediol; (S)-1,2-Propanediol 2-tosylate; (S)-2-Hydroxypropyl 4-methylbenzenesulfonate; (S)-Glycidyl tosylate derivative; (S)-2-Tosyloxy-1-propanol; (S)-α-Tosylglycerol; (S)-2-O-(p-Toluenesulfonyl)glycerol
EINECS	Contact for details

Quality Control

Our (S)-(+)-2-(p-Toluenesulfonate)-1,2-Propanediol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting research and production standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.