Description

(1S,5R)-1-Phenyl-3-Oxabicyclo[3.1.0]Hexan-2-One is a high-purity, chiral bicyclic lactone compound of significant interest in advanced organic synthesis. Its unique fused oxabicyclo[3.1.0]hexane scaffold makes it a valuable and versatile building block for constructing complex molecular architectures. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the creation of advanced, biologically active molecules for crop protection products.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Material Science Precursor: Potential building block for specialty polymers and advanced organic materials with specific optical or structural properties.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry for the construction of strained ring systems.

Basic Information

Product Name	(1S,5R)-1-Phenyl-3-Oxabicyclo[3.1.0]Hexan-2-One
CAS No.	96847-53-9
Molecular Formula	C11H10O2
Molecular Weight	174.20 g/mol
Synonyms	(1S,5R)-1-Phenyl-3-oxabicyclo[3.1.0]hexan-2-one; (1S,5R)-1-Phenyl-3-oxabicyclo[3.1.0]hexane-2-one; (-)-(1S,5R)-1-Phenyl-3-oxabicyclo[3.1.0]hexan-2-one; 1-Phenyl-3-oxabicyclo[3.1.0]hexan-2-one, (1S,5R)-; Bicyclo[3.1.0]hexan-2-one, 1-phenyl-3-oxa-, (1S,5R)-; (1S,5R)-1-Phenyl-3-oxa-bicyclo[3.1.0]hexan-2-one; Chiral Phenyl Oxabicyclohexanone
EINECS	Contact for details

Quality Control

Our (1S,5R)-1-Phenyl-3-Oxabicyclo[3.1.0]Hexan-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC/Chiral HPLC), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.