Description

(1S,2R)-2-(Hydroxymethyl)-1-Phenylcyclopropanecarboxylic Acid is a high-purity chiral cyclopropane derivative of significant importance in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Asymmetric Catalyst Ligand Precursor: Used in the development and synthesis of novel chiral ligands for transition metal catalysis.
• Agrochemical Research: Serves as a building block for creating novel chiral pesticides and herbicides with enhanced efficacy and selectivity.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products and specialty chemicals requiring the cyclopropane motif.
• Material Science Research: Investigated as a monomer or precursor for advanced polymeric materials with specific stereochemical properties.

Basic Information

Product Name	(1S,2R)-2-(Hydroxymethyl)-1-Phenylcyclopropanecarboxylic Acid
CAS No.	96847-51-7
Molecular Formula	C11H12O3
Molecular Weight	192.21 g/mol
Synonyms	(1S,2R)-2-(Hydroxymethyl)-1-phenylcyclopropanecarboxylic acid; (1S,2R)-1-Phenyl-2-(hydroxymethyl)cyclopropanecarboxylic acid; (1S,2R)-1-Phenyl-2-(hydroxymethyl)cyclopropane-1-carboxylic acid; trans-2-(Hydroxymethyl)-1-phenylcyclopropanecarboxylic acid; (1S,2R)-HPCA; Chiral Phenylcyclopropane Carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our (1S,2R)-2-(Hydroxymethyl)-1-Phenylcyclopropanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.