Description

9-(5'-(2-Oxo-1,3,2-Oxazaphosphorinan-2-Yl)-β-Arabinosyl)Adenine is a sophisticated nucleoside analog with a unique oxazaphosphorinane ring system, representing a key intermediate in advanced pharmaceutical research. This compound is valued for its potential to modulate biological pathways, making it a critical building block for developing novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of antiviral and anticancer drug candidates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a probe or substrate in enzymatic studies to investigate nucleotide metabolism and related pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Antiviral Drug Development: Investigated for its potential activity against a range of viral targets due to its modified nucleoside structure.
• Oncology Research: Explored for its role in developing prodrugs or targeted therapies that interfere with DNA/RNA synthesis in cancer cells.
• Academic Synthesis: Employed in university laboratories for teaching and research in advanced organic and bioorganic chemistry.

Basic Information

Product Name	9-(5'-(2-Oxo-1,3,2-Oxazaphosphorinan-2-Yl)-β-Arabinosyl)Adenine
CAS No.	96790-49-7
Molecular Formula	C₁₇H₂₂N₇O₇P
Molecular Weight	467.38 g/mol
Synonyms	9-[5-O-(2-Oxo-1,3,2-oxazaphosphorinan-2-yl)-β-D-arabinofuranosyl]adenine; Cyclophosphamide Arabinoside Adenine Derivative; 9-(5-O-(2-Oxo-1,3,2-oxazaphosphorinan-2-yl)-β-D-arabinofuranosyl)-9H-adenine; 2'-Deoxy-2'-phosphonocytidine Adenine Analog; Ara-C Cyclophosphamide Conjugate; NSC-Derivative 96790-49-7; Adenine Arabinosyl Oxazaphosphorinane Ester
EINECS	Contact for details

Quality Control

Our 9-(5'-(2-Oxo-1,3,2-Oxazaphosphorinan-2-Yl)-β-Arabinosyl)Adenine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant guidelines for advanced pharmaceutical intermediates to support our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.