Description

1-Deoxy-1-[Methyl[3-Phenyl-3-[4-(Trifluoromethyl)Phenoxy]Propyl]Amino]-β-D-Glucopyranuronic Acid is a high-purity, advanced pharmaceutical intermediate with a complex molecular architecture designed for targeted therapeutic applications. This compound matters for its role as a critical building block in the synthesis of novel, high-value active pharmaceutical ingredients (APIs), particularly those targeting metabolic and inflammatory pathways. Pharmaceutical R&D teams and fine chemical manufacturers need this material to develop next-generation drug candidates, leveraging its specific glucopyranuronic acid scaffold and trifluoromethylphenoxy moiety for enhanced bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel SGLT (Sodium-Glucose Linked Transporter) inhibitors and other metabolic disorder therapeutics.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• API Synthesis: Serves as a crucial building block in multi-step synthetic routes for complex, high-potency active pharmaceutical ingredients.
• Biochemical Research: Employed in studies investigating carbohydrate-based drug delivery systems and targeted prodrug development.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	1-Deoxy-1-[Methyl[3-Phenyl-3-[4-(Trifluoromethyl)Phenoxy]Propyl]Amino]-β-D-Glucopyranuronic Acid
CAS No.	96735-71-6
Molecular Formula	C24H26F3NO7
Molecular Weight	497.46 g/mol
Synonyms	1-Deoxy-1-(N-methyl-N-{3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl}amino)-β-D-glucopyranuronic acid; Canagliflozin Impurity; Canagliflozin Related Compound; SGLT2 Inhibitor Intermediate; 1-(3-(4-(Trifluoromethyl)phenoxy)-3-phenylpropyl)(methyl)amino)-1-deoxy-β-D-glucopyranuronic acid; β-D-Glucopyranuronic acid, 1-deoxy-1-[methyl[3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]amino]-; 96735-71-6.
EINECS	Contact for details

Quality Control

Our 1-Deoxy-1-[Methyl[3-Phenyl-3-[4-(Trifluoromethyl)Phenoxy]Propyl]Amino]-β-D-Glucopyranuronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical development. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment. We support development with research-grade to cGMP-grade material, tailored to your project phase.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.