Description

1-Eicosanoyl-3''-n-(Trifluoroacetyl)Kanamycin is a chemically modified derivative of the aminoglycoside antibiotic kanamycin, designed for advanced research and development applications. This semi-synthetic compound is engineered to enhance specific properties such as stability, lipophilicity, or biological activity for targeted studies. It serves as a critical intermediate or reference standard for pharmaceutical researchers, medicinal chemists, and academic institutions focused on antibiotic development, mechanism of action studies, and novel drug conjugate synthesis.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of novel antibiotic derivatives and prodrugs.
• Medicinal Chemistry Studies: Used to investigate structure-activity relationships (SAR) and improve the pharmacokinetic profile of aminoglycoside antibiotics.
• Biochemical Research: Acts as a tool compound for studying bacterial ribosome interactions and mechanisms of antibiotic resistance.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in microbiology and organic synthesis.
• API Intermediate: Potential use as a building block in the controlled synthesis of Active Pharmaceutical Ingredients (APIs) under GMP conditions.

Basic Information

Product Name	1-Eicosanoyl-3''-n-(Trifluoroacetyl)Kanamycin
CAS No.	96695-80-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Kanamycin, 1-eicosanoyl-3''-N-(trifluoroacetyl)-; 3''-Deoxy-3''-N-trifluoroacetyl-1-eicosanoylkanamycin; 1-Eicosanoyl-3''-deoxy-3''-N-trifluoroacetylkanamycin; Kanamycin A 1-eicosanoyl-3''-N-trifluoroacetyl derivative; Trifluoroacetylkanamycin eicosanoate derivative; Research Compound 96695-80-6
EINECS	Contact for details

Quality Control

Our 1-Eicosanoyl-3''-n-(Trifluoroacetyl)Kanamycin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research purposes. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and relevant analytical data. We adhere to high-purity standards suitable for research and development, with specifications available to meet the rigorous demands of pharmaceutical and academic laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.