Description

Ethanone, 1-(2,3-Dichlorocyclobutyl)-, (1Alpha,2Beta,3Beta)- (9Ci) is a specialized chlorinated cyclobutyl ketone derivative, identified by CAS number 96688-35-6, serving as a high-value synthetic intermediate in advanced organic synthesis. This compound is critical for constructing complex molecular architectures, offering precise stereochemistry and functional handles for further chemical elaboration. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) or anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the dichlorocyclobutyl moiety can contribute to unique biological activity.
• Advanced Material Research: Serves as a precursor for specialty polymers or liquid crystals, leveraging its rigid cyclobutane ring structure.
• Chemical Biology Probe Development: Utilized as a scaffold or coupling component in the creation of molecular probes for studying enzyme function or cellular pathways.
• Catalyst Ligand Synthesis: Acts as a starting material for the preparation of novel chiral ligands used in asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	Ethanone, 1-(2,3-Dichlorocyclobutyl)-, (1Alpha,2Beta,3Beta)- (9Ci)
CAS No.	96688-35-6
Molecular Formula	C6H8Cl2O
Molecular Weight	167.03 g/mol
Synonyms	1-(2,3-Dichlorocyclobutyl)ethanone; (1α,2β,3β)-1-(2,3-Dichlorocyclobutyl)ethan-1-one; 2,3-Dichlorocyclobutan-1-yl methyl ketone; 96688-35-6; 1-Acetyl-2,3-dichlorocyclobutane (stereospecific); (1R,2S,3S)-1-(2,3-Dichlorocyclobutyl)ethanone (if absolute configuration is known); Dichlorocyclobutyl methyl ketone
EINECS	Contact for details

Quality Control

Every batch of Ethanone, 1-(2,3-Dichlorocyclobutyl)-, (1Alpha,2Beta,3Beta)- (9Ci) is produced and analyzed under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all critical parameters is provided with each shipment, ensuring full traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.