Description

3-[(tert-Butoxycarbonyl)Amino]Ethyl Methanesulfonate is a high-purity, protected amino alcohol derivative used as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the controlled introduction of aminoethyl moieties under mild conditions while protecting the amine functionality. Pharmaceutical, agrochemical, and specialty chemical R&D teams need it for the development of active pharmaceutical ingredients (APIs), peptide mimetics, and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and neurology.
• Peptide Chemistry: Used in solid-phase peptide synthesis (SPPS) for the incorporation of modified amino acid residues.
• Linker & Conjugation Agent: Facilitates the creation of antibody-drug conjugates (ADCs) and other bioconjugates due to its reactive sulfonate ester group.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides and plant growth regulators.
• Material Science: Monomer or cross-linking agent for the development of functional polymers and hydrogels.
• Protecting Group Strategy: The Boc (tert-butoxycarbonyl) group allows for orthogonal deprotection in multi-step synthetic sequences.

Basic Information

Product Name	3-[(tert-Butoxycarbonyl)Amino]Ethyl Methanesulfonate
CAS No.	96628-67-0
Molecular Formula	C9H19NO5S
Molecular Weight	253.32 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]ethyl methanesulfonate; N-Boc-2-aminoethyl methanesulfonate; 2-(Boc-amino)ethyl mesylate; tert-Butyl N-(2-mesyloxyethyl)carbamate; Boc-NH-CH2-CH2-OSO2CH3; 2-((tert-Butoxycarbonyl)amino)ethyl methanesulfonate; Aminoethyl methanesulfonate Boc-protected
EINECS	Contact for details

Quality Control

Our 3-[(tert-Butoxycarbonyl)Amino]Ethyl Methanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.