Description

7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-1,8-Naphthyridine-3-Carboxylic Acid Ethyl Ester is a high-purity pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of advanced fluoroquinolone antibiotics, enabling the development of next-generation antimicrobial agents. It is essential for R&D laboratories and manufacturing facilities in the pharmaceutical and fine chemical sectors seeking reliable, high-quality raw materials for active pharmaceutical ingredient (API) production.

Application

• Key Intermediate for Fluoroquinolone Antibiotics: A vital precursor in the synthesis of novel broad-spectrum antibacterial agents.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the discovery and optimization of new antimicrobial compounds.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in scaled-up production processes for final drug substances.
• Process Chemistry & Method Development: Serves as a standard for developing and validating new synthetic routes in fine chemical production.
• Reference Standard: Used in analytical laboratories for quality control, method validation, and regulatory compliance testing.

Basic Information

Product Name	7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-1,8-Naphthyridine-3-Carboxylic Acid Ethyl Ester
CAS No.	96568-07-9
Molecular Formula	C15H12ClFN2O3
Molecular Weight	322.72 g/mol
Synonyms	Ethyl 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate; 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid ethyl ester; 1,8-Naphthyridine-3-carboxylic acid, 7-chloro-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-, ethyl ester; 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid ethyl ester; 96568-07-9; Ethyl 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our 7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-1,8-Naphthyridine-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets stringent specifications for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements, including ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to minimize exposure to atmospheric moisture and light to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.