Description

10-Oxocodeine 6-Acetate is a semi-synthetic derivative of thebaine, serving as a key intermediate in advanced pharmaceutical research and synthesis. This compound is valued for its specific structural modifications, which are crucial for developing novel opioid receptor ligands and exploring structure-activity relationships. It is primarily utilized by research institutions and pharmaceutical development laboratories focused on neuropharmacology and analgesic discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the research and development of new opioid analgesic compounds and receptor modulators.
• Medicinal Chemistry Research: Used in academic and industrial labs for studying the structure-activity relationship (SAR) of morphinan derivatives.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in forensic and pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating the biochemical pathways and metabolism of opioid compounds.
• Process Chemistry Development: Used in scaling up and optimizing synthetic routes for complex pharmaceutical actives.

Basic Information

Product Name	10-Oxocodeine 6-Acetate
CAS No.	96562-83-3
Molecular Formula	C21H23NO5
Molecular Weight	369.41 g/mol
Synonyms	6-Acetyl-10-oxocodeine; 10-Oxo-6-O-acetylcodeine; 6-Acetoxy-10-oxocodeine; Thebaine-6-acetate-10-one; 10-Oxocodeine acetate; 6-O-Acetyl-10-oxocodeine; 10-Ketocodeine 6-acetate
EINECS	Contact for details

Quality Control

Our 10-Oxocodeine 6-Acetate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.