Description

(2S,3R)-3-(3,4-Dihydroxyphenyl)-3-Hydroxy-2-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Propionic Acid is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. Its complex stereochemistry and functional groups make it a critical building block for the development of novel active pharmaceutical ingredients (APIs). This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the production of complex, optically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of complex APIs, particularly those targeting neurological and cardiovascular systems.
• Asymmetric Synthesis: Utilized as a building block in stereoselective organic synthesis to introduce specific (2S,3R) stereochemistry into target molecules.
• Biochemical Research: Serves as a precursor or reference standard in biochemical pathway studies and enzyme inhibition research.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, advanced materials, and other high-value compounds requiring precise chiral control.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.

Basic Information

Item	Details
Product Name	(2S,3R)-3-(3,4-Dihydroxyphenyl)-3-Hydroxy-2-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Propionic Acid
CAS No.	96561-53-4
Molecular Formula	C17H13NO7
Molecular Weight	343.29 g/mol
Synonyms	(2S,3R)-3-(3,4-Dihydroxyphenyl)-3-hydroxy-2-(1,3-dioxoisoindolin-2-yl)propanoic acid; (2S,3R)-3-(3,4-Dihydroxyphenyl)-3-hydroxy-2-(phthalimido)propionic acid; NSC 339586; L-3-(3,4-Dihydroxyphenyl)-3-hydroxy-2-phthalimidopropionic acid; (2S,3R)-3,4-Dihydroxyphenylserine phthalimide derivative; Phthaloyl-DOPS derivative
EINECS	Contact for details

Quality Control

Our (2S,3R)-3-(3,4-Dihydroxyphenyl)-3-Hydroxy-2-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles are available for every lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and light-sensitive nature, the material should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and opened only in a moisture-controlled environment to prevent degradation and oxidation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.