Description

3Alpha-Trimethylsilyloxy-5Beta-19-Norandrostan-17-One is a high-purity, advanced steroid intermediate with a protected hydroxyl group, essential for precise synthetic pathways. This compound matters for its role as a critical building block in the research and development of novel pharmaceutical actives, enabling complex molecular modifications. It is primarily needed by R&D laboratories and manufacturers in the pharmaceutical and biotechnology sectors for the synthesis of specialized steroid-based therapeutics and reference standards.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel steroid-derived drug candidates and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial R&D for exploring new synthetic routes, structure-activity relationships (SAR), and metabolic studies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Employed in scale-up and process optimization for the production of specialized steroid compounds under GMP conditions.
• Biochemical Research: Utilized in studies investigating steroid hormone pathways, receptor binding, and enzyme inhibition.

Basic Information

Product Name	3Alpha-Trimethylsilyloxy-5Beta-19-Norandrostan-17-One
CAS No.	96551-50-7
Molecular Formula	C22H38O2Si
Molecular Weight	362.63 g/mol
Synonyms	3α-Trimethylsilyloxy-5β-19-norandrostan-17-one; 3α-(Trimethylsilyloxy)-5β-estran-17-one; 5β-Estran-17-one, 3α-(trimethylsilyloxy)-; 19-Norandrostan-17-one, 3α-(trimethylsilyloxy)-5β-; TMS-Protected 3α-Hydroxy-5β-19-Norandrostan-17-One
EINECS	Contact for details

Quality Control

Our 3Alpha-Trimethylsilyloxy-5Beta-19-Norandrostan-17-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.