Description

Norethindrone-3-Ethyldienolether CAS NO 96487-85-3 is a high-purity pharmaceutical intermediate, a key synthetic precursor in the production of steroid-based active pharmaceutical ingredients (APIs). Its precise chemical structure is critical for ensuring the efficacy and safety of the final drug products derived from it. This compound is essential for manufacturers in the pharmaceutical and fine chemical industries engaged in the synthesis of hormonal contraceptives and other therapeutic steroids.

Application

• Primary Intermediate in the synthesis of Norethindrone (Norethisterone) and related progestin APIs.
• Key Building Block for the manufacture of hormonal contraceptive drugs and hormone replacement therapies (HRT).
• Research & Development of novel steroid-based therapeutics in pharmaceutical laboratories.
• Fine Chemical Synthesis for creating specialized steroid derivatives for biological testing.
• Reference Standard for quality control and analytical method development in API production.

Basic Information

Product Name	Norethindrone-3-Ethyldienolether
CAS No.	96487-85-3
Molecular Formula	C22H28O2
Molecular Weight	324.46 g/mol
Synonyms	19-Nor-17α-pregn-4-en-20-yn-3-one, 17-(Ethylidenedioxy)-; 17-Ethylenedioxy-19-nor-17α-pregn-4-en-20-yn-3-one; 3,20-Dioxo-19-nor-17α-pregna-4-en-17-yl ethyl acetal; Norethisterone 3,17-acetonide (common misnomer); Norethindrone 3-ethylenedioxy ketal; Norethisterone 3-ethylenedioxy ether; Precursor to Norethindrone
EINECS	Contact for details

Quality Control

Our Norethindrone-3-Ethyldienolether is manufactured under strict quality management systems to meet the exacting standards of pharmaceutical ingredient production. Each batch is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via HPLC, to ensure consistent quality and traceability. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.