Description

5'-Hydroxy-2''-Demethyldihydrostreptomycin is a chemically modified derivative of the classic aminoglycoside antibiotic, dihydrostreptomycin. This compound is of significant interest in pharmaceutical research and development, particularly for the study of structure-activity relationships and the synthesis of novel antibiotic analogs. It serves as a critical intermediate and reference standard for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors seeking to develop or analyze advanced antimicrobial agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel aminoglycoside antibiotic derivatives.
• Biochemical Research: Used as a reference standard in studies investigating antibiotic mechanisms of action, resistance, and bacterial ribosome interaction.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.
• Life Science Tools: Utilized in the development of diagnostic assays and research kits focused on bacterial genetics and antibiotic susceptibility testing.
• Academic Research: Employed in university and institutional labs for fundamental research in medicinal chemistry and microbiology.

Basic Information

Product Name	5'-Hydroxy-2''-Demethyldihydrostreptomycin
CAS No.	96480-49-8
Molecular Formula	C21H41N7O12
Molecular Weight	583.60 g/mol
Synonyms	5'-Hydroxy-2''-demethyl-dihydrostreptomycin; Dihydrostreptomycin, 5'-hydroxy-2''-demethyl-; 2''-Demethyl-5'-hydroxydihydrostreptomycin; 5'-Hydroxy-2''-demethylstreptomycin derivative; Antibiotic research intermediate; Aminoglycoside research chemical; CAS 96480-49-8
EINECS	Contact for details

Quality Control

Our 5'-Hydroxy-2''-Demethyldihydrostreptomycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.