Description

5-Oxo-1-(1-Phenyl-Ethyl)-Pyrrolidine-3-Carboxylic Acid is a high-purity pyrrolidine derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique structure, featuring a carboxylic acid group and a chiral center, makes it invaluable for constructing complex molecules with specific stereochemistry. This compound is primarily sought after by research institutions and pharmaceutical manufacturers for the development of novel active pharmaceutical ingredients (APIs), fine chemicals, and specialized ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of new drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapies.
• Asymmetric Synthesis: Used as a precursor or catalyst ligand in stereoselective reactions to create enantiomerically pure compounds.
• Fine Chemical Production: Serves as a building block for synthesizing complex agrochemicals, flavors, and fragrances.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Peptidomimetics: Its pyrrolidine core is utilized in the design and synthesis of peptide mimics for biochemical research.

Basic Information

Product Name	5-Oxo-1-(1-Phenyl-Ethyl)-Pyrrolidine-3-Carboxylic Acid
CAS No.	96449-93-3
Molecular Formula	C13H15NO3
Molecular Weight	233.26 g/mol
Synonyms	1-(1-Phenylethyl)-5-oxopyrrolidine-3-carboxylic acid; 3-Carboxy-1-(α-methylbenzyl)-2-pyrrolidinone; 1-(α-Methylbenzyl)-5-oxo-3-pyrrolidinecarboxylic acid; 5-Oxo-1-(α-methylbenzyl)pyrrolidine-3-carboxylic acid; (R/S)-5-Oxo-1-(1-phenylethyl)pyrrolidine-3-carboxylic acid; Pyrrolidine-3-carboxylic acid, 5-oxo-1-(1-phenylethyl)-; 96449-93-3 (CAS)
EINECS	Contact for details

Quality Control

Our 5-Oxo-1-(1-Phenyl-Ethyl)-Pyrrolidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical research and fine chemical synthesis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (or as specified)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.