Description

[S,(+)]-6β-[(1S,2S)-1-Acetyloxy-2-Hydroxy-2-Phenylethyl]-5,6-Dihydro-2H-Pyran-2-One is a high-purity, chiral lactone derivative of significant interest in advanced organic synthesis. Its complex stereochemistry makes it a valuable chiral building block for the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for complex, stereospecific drug molecules.
• Asymmetric Synthesis: Used as a starting material or advanced intermediate in catalytic and stoichiometric asymmetric synthesis to introduce defined stereocenters.
• Agrochemical Research: Serves as a precursor in the synthesis of chiral active ingredients for crop protection products, where specific stereochemistry can influence efficacy and environmental profile.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, including flavors, fragrances, and advanced materials requiring precise molecular architecture.
• Academic & Industrial R&D: A critical reagent for methodological development in organic chemistry, enabling studies in total synthesis and new reaction pathways.

Basic Information

Product Name	[S,(+)]-6β-[(1S,2S)-1-Acetyloxy-2-Hydroxy-2-Phenylethyl]-5,6-Dihydro-2H-Pyran-2-One
CAS No.	96422-53-6
Molecular Formula	C15H16O5
Molecular Weight	276.28 g/mol
Synonyms	(+)-6β-[(1S,2S)-1-Acetoxy-2-hydroxy-2-phenylethyl]-5,6-dihydro-2H-pyran-2-one; (S)-6β-[(1S,2S)-1-Acetyloxy-2-hydroxy-2-phenylethyl]-5,6-dihydro-2H-pyran-2-one; 6β-[(1S,2S)-1-Acetoxy-2-hydroxy-2-phenylethyl]-5,6-dihydro-(2H)-pyran-2-one; (S)-6β-[(1S,2S)-1-Acetoxy-2-hydroxy-2-phenylethyl]-5,6-dihydro-2H-pyran-2-one; 96422-53-6; Dihydro-2H-pyran-2-one derivative; Chiral lactone intermediate
EINECS	Contact for details

Quality Control

Our production of [S,(+)]-6β-[(1S,2S)-1-Acetyloxy-2-Hydroxy-2-Phenylethyl]-5,6-Dihydro-2H-Pyran-2-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.