Description

(6R)-6-[(1R,2R)-1,2-Dihydroxy-2-Phenylethyl]-5,6-Dihydro-2H-Pyran-2-One is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its precise stereochemistry makes it a valuable precursor for the development of complex, biologically active molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for drugs targeting specific stereochemical pathways.
• Asymmetric Synthesis: Utilized as a building block for constructing complex molecules with defined stereocenters, essential for creating enantiomerically pure compounds.
• Medicinal Chemistry Research: Serves as a scaffold or precursor in the discovery and optimization of novel drug candidates within academic and industrial R&D laboratories.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals, flavors, fragrances, and advanced materials where high stereochemical fidelity is required.
• Catalyst and Ligand Development: Can be employed in the synthesis of novel chiral catalysts or ligands used to control stereoselectivity in chemical reactions.

Basic Information

Product Name	(6R)-6-[(1R,2R)-1,2-Dihydroxy-2-Phenylethyl]-5,6-Dihydro-2H-Pyran-2-One
CAS No.	96422-52-5
Molecular Formula	C13H14O4
Molecular Weight	234.25 g/mol
Synonyms	(6R,1'R,2'R)-6-(1',2'-Dihydroxy-2'-phenylethyl)-5,6-dihydro-2H-pyran-2-one; (6R)-6-[(1R,2R)-1,2-Dihydroxy-2-phenylethyl]-5,6-dihydro-2H-pyran-2-one; Dihydro-2H-pyran-2-one, 6-[(1R,2R)-1,2-dihydroxy-2-phenylethyl]-5,6-dihydro-, (6R)-; Chiral Dihydroxyphenyl Dihydropyranone; (R,R,R)-Dihydroxyethylphenyl Dihydropyranone
EINECS	Contact for details

Quality Control

Our (6R)-6-[(1R,2R)-1,2-Dihydroxy-2-Phenylethyl]-5,6-Dihydro-2H-Pyran-2-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.