Description

2-Methyl-4-[(E)-2-[(5,6,7,8-Tetrahydro-5,5,8,8-Tetramethylnaphthalen)-2-Yl]-1-Propenyl]Benzoic Acid is a high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. Its complex, polycyclic structure makes it a valuable building block for the synthesis of novel therapeutic agents, particularly in the fields of oncology and dermatology. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel retinoid analogs and other receptor-targeting drug candidates.
• Research & Development: Used in academic and industrial labs for structure-activity relationship (SAR) studies and medicinal chemistry programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a critical building block in multi-step synthetic routes for complex APIs.
• Dermatological Agent Development: Explored for the creation of new compounds targeting skin conditions and cellular differentiation pathways.
• Chemical Biology Probes: Utilized in the development of molecular probes to study nuclear receptor signaling and gene expression.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing of specialized, high-value organic molecules.

Basic Information

Product Name	2-Methyl-4-[(E)-2-[(5,6,7,8-Tetrahydro-5,5,8,8-Tetramethylnaphthalen)-2-Yl]-1-Propenyl]Benzoic Acid
CAS No.	96409-35-7
Molecular Formula	C25H30O2
Molecular Weight	362.51 g/mol
Synonyms	4-[(1E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)-1-propen-1-yl]-2-methylbenzoic Acid; TTNPB Acid; Arotinoid Acid; (E)-4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)propen-1-yl]-2-methylbenzoic Acid; 2-Methyl-4-[(E)-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic Acid (common misnomer); AGN 190168 Acid; Retinoid-related molecule intermediate.
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-[(E)-2-[(5,6,7,8-Tetrahydro-5,5,8,8-Tetramethylnaphthalen)-2-Yl]-1-Propenyl]Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and compliance data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.