Description

Luteolin 7-Diglucuronide is a bioactive flavonoid glucuronide, a key metabolite of the dietary flavonoid luteolin. This compound matters for its significant role as a reference standard in analytical chemistry and for research into its potent antioxidant and anti-inflammatory properties. It is primarily needed by pharmaceutical R&D laboratories, nutraceutical manufacturers, and academic institutions conducting research on natural product metabolism and bioactivity.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for the quantification and identification of luteolin metabolites in drug development and pharmacokinetic studies.
• Nutraceutical & Functional Food Research: Serves as a key analytical marker for standardizing herbal extracts and validating the bioavailability of luteolin in dietary supplements.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate its mechanisms of action, including antioxidant, anti-inflammatory, and potential chemopreventive activities.
• Analytical Method Development: Essential for developing and validating HPLC, LC-MS, and other chromatographic methods for the analysis of flavonoids and their conjugates in complex matrices.
• Cosmeceutical Ingredient Research: Studied for its potential skin-protective effects against UV-induced oxidative stress and inflammation in advanced cosmetic formulations.

Basic Information

Product Name	Luteolin 7-Diglucuronide
CAS No.	96400-45-2
Molecular Formula	C27H26O18
Molecular Weight	638.49 g/mol
Synonyms	Luteolin 7-O-diglucuronide; Luteolin-7-diglucuronide; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 2-({[(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-({[(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}carbonyl)oxan-2-yl]oxy}carbonyl)oxy]-3,4,5-trihydroxy-6-methyloxane-2-carboxylate; Luteolin 7-O-β-D-diglucuronide; Luteolin diglucuronide
EINECS	Contact for details

Quality Control

Our Luteolin 7-Diglucuronide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the stringent requirements for research and reference standard applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. For long-term storage, consider storing desiccated at -20°C. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤5.0%
Residue on Ignition	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.