Description

(S)-Methyl 3-(Benzyloxycarbonylamino)-5-Methylhexanoate is a high-purity chiral building block and protected amino acid derivative essential for advanced organic synthesis. This compound matters as a key intermediate in the production of complex pharmaceutical molecules, particularly peptides and peptidomimetics, where its defined stereochemistry is critical for biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Peptide Chemistry: Serves as a protected amino acid ester for solid-phase and solution-phase peptide synthesis.
• Protease Inhibitor Development: Used in the research and production of enzyme inhibitors targeting various disease pathways.
• Asymmetric Synthesis: Employed as a starting material or intermediate in stereoselective catalytic reactions.
• Bioconjugation & Labeling: Useful for creating modified biomolecules for diagnostic and therapeutic applications.
• Academic & Industrial R&D: A valuable reagent for medicinal chemistry programs and process chemistry optimization in laboratory and pilot-scale settings.

Basic Information

Product Name	(S)-Methyl 3-(Benzyloxycarbonylamino)-5-Methylhexanoate
CAS No.	96386-94-6
Molecular Formula	C16H23NO4
Molecular Weight	293.36 g/mol
Synonyms	(S)-Methyl 3-((Benzyloxy)carbonylamino)-5-methylhexanoate; (S)-Methyl 3-(Cbz-amino)-5-methylhexanoate; (S)-3-[(Benzyloxycarbonyl)amino]-5-methylhexanoic acid methyl ester; Cbz-L-leucine methyl ester derivative; Z-L-Leu-OMe (related derivative); Methyl (3S)-3-[[(benzyloxy)carbonyl]amino]-5-methylhexanoate; (S)-5-Methyl-3-[(phenylmethoxy)carbonylamino]hexanoic acid methyl ester
EINECS	Contact for details

Quality Control

Our (S)-Methyl 3-(Benzyloxycarbonylamino)-5-Methylhexanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and cGMP-grade production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.