Description

Fmoc-L-Ser(β-D-Galac4)-Oh is a specialized, protected amino acid derivative designed for advanced solid-phase peptide synthesis (SPPS). This compound is critical for the precise and efficient construction of complex glycopeptides, where the serine-linked galactose moiety must be preserved during synthesis. It is an essential building block for researchers and manufacturers in pharmaceutical development, particularly for creating novel therapeutic peptides and glycoconjugate vaccines.

Application

• Glycopeptide Synthesis: A key protected intermediate for the automated synthesis of O-linked glycopeptides.
• Pharmaceutical R&D: Used in the discovery and development of novel peptide-based therapeutics targeting cancer, metabolic diseases, and infections.
• Vaccine Development: Essential for constructing antigenic glycopeptide sequences used in conjugate vaccine candidates.
• Chemical Biology Studies: Employed to probe protein-glycan interactions and enzyme functions.
• Bioconjugation: Serves as a precursor for creating site-specifically glycosylated proteins and other biomolecules.
• Process Development: Used in scaling up the production of clinical-grade glycopeptide APIs.

Basic Information

Product Name	Fmoc-L-Ser(β-D-Galac4)-Oh
CAS No.	96383-44-7
Molecular Formula	C30H29NO11
Molecular Weight	579.55 g/mol
Synonyms	Fmoc-Ser(Gal(Ac)4)-OH; N-α-Fmoc-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-L-serine; Fmoc-L-Serine, O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-, 9-fluorenylmethyl ester; Fmoc-Ser(Ac4Gal-β)-OH; Fmoc-O-(tetra-O-acetyl-β-D-galactopyranosyl)-L-serine; Fmoc-L-Ser(β-D-Gal(Ac)4)-OH; Fmoc-Ser(β-D-Galactopyranosyl tetraacetate)-OH
EINECS	Contact for details

Quality Control

Our Fmoc-L-Ser(β-D-Galac4)-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive research and production applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a dry environment before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Optical Rotation	-15° to -25° (c=1 in DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.