Description

1,2-Dipalmitoyl-3-Dimethylammonium-Propane (CAS NO 96326-74-8) is a synthetic, cationic phospholipid analog that serves as a critical component in advanced formulation science. Its primary value lies in its ability to form stable cationic liposomes, which are essential for enhancing cellular delivery and uptake. This compound is particularly vital for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing next-generation drug delivery systems, gene therapies, and vaccine adjuvants.

Application

• Liposomal Drug Delivery: A key cationic lipid for formulating stable liposomes to encapsulate and deliver hydrophobic or nucleic acid-based therapeutics.
• Gene Transfection & Therapy: Used as a critical component in non-viral transfection reagents (lipoplexes) for the efficient delivery of DNA, siRNA, or mRNA into cells.
• Vaccine Adjuvant Systems: Employed in the development of cationic liposome-based adjuvants to enhance immune response to vaccine antigens.
• Biophysical & Membrane Research: Serves as a model cationic lipid for studying lipid bilayer properties, membrane fusion, and cell-liposome interactions.
• Cosmetic & Dermal Formulations: Incorporated into advanced cosmetic products for its encapsulation and skin penetration enhancement properties.
• Diagnostic Reagent Preparation: Used in the formulation of lipid-based carriers for diagnostic imaging agents.

Basic Information

Product Name	1,2-Dipalmitoyl-3-Dimethylammonium-Propane
CAS No.	96326-74-8
Molecular Formula	C40H82NO4P
Molecular Weight	672.06 g/mol
Synonyms	DODAP; 1,2-Dipalmitoyl-sn-glycero-3-ethylphosphocholine (common misnomer); 1,2-Dihexadecanoyl-3-(dimethylammonium)propane; Cationic lipid DODAP; 3-(Dimethylamino)propane-1,2-diyl dipalmitate; 1,2-Dipalmitoyl-rac-glycero-3-ethylphosphocholine; Dipalmitoyl dimethylammonium propane; DP-DAP
EINECS	Contact for details

Quality Control

Our 1,2-Dipalmitoyl-3-Dimethylammonium-Propane is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical development. A Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, consider sealing under argon or nitrogen. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (TLC)	Single spot
Melting Point	Contact for details
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.