Description

L-Proline, 4-[(Aminocarbonyl)Oxy]-, trans- (9Ci) is a specialized, high-purity derivative of the amino acid L-proline, featuring a carbamoyloxy substitution at the 4-position. This compound is valued for its role as a key chiral building block and intermediate in advanced organic synthesis, particularly for pharmaceuticals and bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially in protease inhibitor and peptidomimetic drug development.
• Agrochemical Research: Used in the design and synthesis of advanced, biologically active compounds for crop protection and pest management.
• Peptide Chemistry: Serves as a modified proline residue for constructing specialized peptides with enhanced stability or specific biological activity.
• Bioconjugation & Probe Development: Utilized in creating labeled compounds and molecular probes for biochemical and diagnostic research applications.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in stereoselective catalytic reactions to produce enantiomerically pure compounds.
• Fine Chemical Manufacturing: An important intermediate for producing custom chemicals and specialty materials requiring high stereochemical fidelity.

Basic Information

Product Name	L-Proline, 4-[(Aminocarbonyl)Oxy]-, trans- (9Ci)
CAS No.	96314-74-8
Molecular Formula	C7H12N2O4
Molecular Weight	188.18 g/mol
Synonyms	trans-4-(Aminocarbonyloxy)-L-proline; 4-O-Carbamoyl-L-hydroxyproline; (2S,4R)-4-(Carbamoyloxy)pyrrolidine-2-carboxylic acid; L-4-Hydroxyproline carbamate; 4-Carbamoyloxy-L-proline; 4-OCam-L-Hyp; 4-(Aminocarbonyloxy)-L-proline
EINECS	Contact for details

Quality Control

Our L-Proline, 4-[(Aminocarbonyl)Oxy]-, trans- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.