Description

1,3,5-Tri-o-Acetyl-2-Deoxy-α-D-Erythro-Pentofuranose is a key acetylated sugar derivative and a vital protected intermediate in nucleoside and carbohydrate chemistry. Its primary value lies in enabling the controlled synthesis of complex molecules by providing reactive sites for further functionalization while protecting sensitive hydroxyl groups. This compound is essential for researchers and manufacturers in the pharmaceutical industry, particularly for the development of antiviral and anticancer nucleoside analogs, as well as for advanced carbohydrate synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of modified nucleosides and nucleotides used in antiviral and anticancer therapies.
• Carbohydrate Chemistry Research: Serves as a protected precursor for the synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics.
• Prodrug Development: Used in the design and synthesis of prodrugs to enhance the bioavailability and stability of active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Employed in the creation of labeled sugars and metabolic probes for studying biological pathways and enzyme mechanisms.
• Process Development & Scale-up: A reliable starting material for process chemistry teams scaling up the production of nucleoside-based active ingredients under GMP conditions.

Basic Information

Product Name	1,3,5-Tri-o-Acetyl-2-Deoxy-α-D-Erythro-Pentofuranose
CAS No.	96291-74-6
Molecular Formula	C11H16O7
Molecular Weight	260.24 g/mol
Synonyms	2-Deoxy-1,3,5-tri-O-acetyl-α-D-erythro-pentofuranose; 1,3,5-Tri-O-acetyl-2-deoxy-α-D-ribofuranose; 2-Deoxy-α-D-ribofuranose 1,3,5-triacetate; Triacetyl-2-deoxy-α-D-ribofuranose; 2-Deoxy-α-D-erythro-pentofuranose 1,3,5-triacetate; α-D-2-Deoxyribofuranose 1,3,5-triacetate; 2-Deoxy-α-D-ribofuranose triacetate
EINECS	Contact for details

Quality Control

Our 1,3,5-Tri-o-Acetyl-2-Deoxy-α-D-Erythro-Pentofuranose is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. Certificates of Analysis (COA) are available for every batch, and custom specifications can be developed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.