Description

2-[2,3-Dihydro-7-Hydroxy-2-(4-Hydroxy-3-Methoxyphenyl)-3-(Hydroxymethyl)Benzofuran-4-Yl]-2,3-Dihydro-5,7-Dihydroxy-4H-1-Benzopyran-4-One is a complex polyphenolic compound belonging to the class of flavonolignans, known for its significant biological activity. This high-purity chemical is critical for research and development in the pharmaceutical and nutraceutical sectors, where precise molecular structure is paramount for efficacy studies. It serves as a valuable reference standard and a key intermediate for scientists and manufacturers focused on developing novel therapeutics and high-value natural product derivatives.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and purity testing of active pharmaceutical ingredients (APIs) and herbal extracts in quality control laboratories.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate its pharmacological properties, such as antioxidant, anti-inflammatory, and hepatoprotective activities.
• Nutraceutical Development: Serves as a key marker compound for the standardization and quality assurance of complex botanical dietary supplements, ensuring product consistency and potency.
• Organic Synthesis Intermediate: Utilized as a sophisticated building block in the synthesis of novel analogs and derivatives for structure-activity relationship (SAR) studies in medicinal chemistry.
• Analytical Method Development: Acts as a critical standard for developing and validating analytical methods, particularly High-Performance Liquid Chromatography (HPLC) and Liquid Chromatography-Mass Spectrometry (LC-MS) protocols.

Basic Information

Product Name	2-[2,3-Dihydro-7-Hydroxy-2-(4-Hydroxy-3-Methoxyphenyl)-3-(Hydroxymethyl)Benzofuran-4-Yl]-2,3-Dihydro-5,7-Dihydroxy-4H-1-Benzopyran-4-One
CAS No.	96291-04-2
Molecular Formula	C31H26O11
Molecular Weight	574.53 g/mol
Synonyms	Silymarin Impurity; Silybin Impurity; Flavonolignan Derivative; 2-[3,4-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-7-hydroxy-2,3-dihydro-1-benzofuran-4-yl]-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one; 4H-1-Benzopyran-4-one, 2-[2,3-dihydro-7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-4-benzofuranyl]-2,3-dihydro-5,7-dihydroxy-; A compound related to Silychristin/Silydianin isomers.
EINECS	Contact for details

Quality Control

Our 2-[2,3-Dihydro-7-Hydroxy-2-(4-Hydroxy-3-Methoxyphenyl)-3-(Hydroxymethyl)Benzofuran-4-Yl]-2,3-Dihydro-5,7-Dihydroxy-4H-1-Benzopyran-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, MS, NMR), to ensure it meets the stringent requirements for research and reference standard applications. A detailed Certificate of Analysis (COA) specifying batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.