Description

Benzene, 5-(Chloromethyl)-1,2,3-Tris(Phenylmethoxy)- is a specialized aromatic compound that serves as a crucial protected intermediate in advanced organic synthesis. Its value lies in its multi-functional structure, featuring a reactive chloromethyl group and three benzyl-protected hydroxyl groups, enabling precise, multi-step chemical transformations. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing complex molecules, such as active pharmaceutical ingredients (APIs) and sophisticated ligands.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used as a versatile building block for constructing complex aromatic and heterocyclic compounds in research and development.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in catalysis and material science.
• Polymer Chemistry: Can be utilized as a monomer or cross-linking agent in the development of specialty polymers with specific functional properties.
• Academic and Industrial R&D: Employed in research laboratories for methodological development and exploring new synthetic pathways.
• Agrochemical Intermediate: Potential use in the synthesis of advanced, high-value crop protection agents.

Basic Information

Product Name	Benzene, 5-(Chloromethyl)-1,2,3-Tris(Phenylmethoxy)-
CAS No.	96277-83-7
Molecular Formula	C28H25ClO3
Molecular Weight	444.95 g/mol
Synonyms	1,2,3-Tris(benzyloxy)-5-(chloromethyl)benzene; 5-(Chloromethyl)-1,2,3-tris(benzyloxy)benzene; 3,4,5-Tris(benzyloxy)benzyl chloride; 1,2,3-Tris-O-benzyl-5-chloromethylbenzene; Gallic acid tris-benzyl ether chloromethyl derivative; Tris-O-benzylgalloyl chloride (common name); Protected gallic acid chloromethyl derivative
EINECS	Contact for details

Quality Control

Our Benzene, 5-(Chloromethyl)-1,2,3-Tris(Phenylmethoxy)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.