Description

(R)-Methyl 2-(((Benzyloxy)Carbonyl)Amino)-3-((tert-Butoxycarbonyl)Amino)Propanoate is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound matters as a critical chiral building block for the controlled construction of complex peptides and peptidomimetics, offering precise stereochemistry and orthogonal protecting groups. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including protease inhibitors and bioactive peptides.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Solid-Phase Peptide Synthesis (SPPS): Used for the controlled, sequential incorporation of specific amino acid residues, leveraging its orthogonal Cbz and Boc protecting groups.
• Protease Inhibitor Development: Serves as a core structural component in the synthesis of inhibitors targeting specific enzymes.
• Chemical Biology Research: Employed in the synthesis of labeled peptides, peptide libraries, and molecular probes for studying biological mechanisms.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in the enantioselective synthesis of complex natural products and non-natural amino acids.

Basic Information

Product Name	(R)-Methyl 2-(((Benzyloxy)Carbonyl)Amino)-3-((tert-Butoxycarbonyl)Amino)Propanoate
CAS No.	96136-12-8
Molecular Formula	C17H24N2O6
Molecular Weight	352.38 g/mol
Synonyms	Methyl (2R)-2-{[(benzyloxy)carbonyl]amino}-3-[(tert-butoxycarbonyl)amino]propanoate; (R)-Methyl N-Cbz-N'-Boc-2,3-diaminopropionate; (R)-Methyl Nα-Cbz-Nβ-Boc-2,3-diaminopropanoate; (R)-Methyl 2-(N-Cbz-amino)-3-(N-Boc-amino)propionate; (R)-Cbz-Dap(Boc)-OMe; (R)-2,3-Diaminopropionic Acid Derivative; Boc-Dap(Cbz)-OMe (R-isomer)
EINECS	Contact for details

Quality Control

Our (R)-Methyl 2-(((Benzyloxy)Carbonyl)Amino)-3-((tert-Butoxycarbonyl)Amino)Propanoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.