Description

1-(2-(Bis(4-Fluorophenyl)Methoxy)Ethyl)-4-Phenyl-4-Piperidinol Hydrochloride is a high-purity pharmaceutical intermediate and research chemical of significant interest in medicinal chemistry. Its value lies in its role as a key synthetic precursor for the development of novel therapeutic agents targeting the central nervous system. This compound is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and advanced chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of potential neuropharmacological agents and other specialized active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop and optimize new chemical entities with targeted biological activity.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	1-(2-(Bis(4-Fluorophenyl)Methoxy)Ethyl)-4-Phenyl-4-Piperidinol Hydrochloride
CAS No.	96122-79-1
Molecular Formula	C26H27F2NO2·HCl
Molecular Weight	468.0 g/mol (approx.)
Synonyms	4-Phenyl-1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-piperidinol hydrochloride; 1-(2-(Bis(p-fluorophenyl)methoxy)ethyl)-4-phenyl-4-piperidinol HCl; 4-Phenyl-1-[2-[bis(4-fluorophenyl)methoxy]ethyl]piperidin-4-ol hydrochloride; Loperamide intermediate; Loperamide related compound; 96122-79-1; UNII-9Q9K3S001R
EINECS	Contact for details

Quality Control

Our 1-(2-(Bis(4-Fluorophenyl)Methoxy)Ethyl)-4-Phenyl-4-Piperidinol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.