Description

Side Chain For Meropenem CAS NO 96034-64-9 is a critical pharmaceutical intermediate, specifically designed for the synthesis of the broad-spectrum carbapenem antibiotic, Meropenem. This high-purity building block is essential for ensuring the final API's efficacy, stability, and compliance with stringent pharmacopeial standards. It is primarily required by manufacturers in the active pharmaceutical ingredient (API) and fine chemical sectors for the production of sterile injectable antibiotics.

Application

• Primary Intermediate for Meropenem API Synthesis: The essential chemical building block in the multi-step production of the antibiotic Meropenem.
• Fine Chemical Manufacturing: Used in advanced organic synthesis for creating complex β-lactam structures.
• Pharmaceutical Research & Development (R&D): Serves as a key starting material in the development of new carbapenem analogs and process optimization studies.
• Contract Manufacturing Organizations (CMOs): Supplied to CMOs specializing in antibiotic production under current Good Manufacturing Practice (cGMP) guidelines.
• Generic Drug Production: A vital raw material for manufacturers producing generic versions of Meropenem injections.

Basic Information

Product Name	Side Chain For Meropenem
CAS No.	96034-64-9
Molecular Formula	C12H20N2O5S
Molecular Weight	304.36 g/mol
Synonyms	(2S,4S)-2-[(Dimethylamino)carbonyl]-4-mercapto-1-(2,2-dimethylpropanoyl)pyrrolidine; Meropenem Side Chain; Meropenem Intermediate; 1-(2,2-Dimethylpropanoyl)-4-mercapto-2-[(dimethylamino)carbonyl]pyrrolidine; (4S)-2-[(Dimethylamino)carbonyl]-4-mercapto-1-pivaloylpyrrolidine; Pivaloyloxymethyl (4S,5S,6S)-3-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate side chain precursor
EINECS	Contact for details

Quality Control

Our Side Chain For Meropenem is produced under strict quality management systems to meet the exacting standards of pharmaceutical synthesis. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with in-house specifications aligned with ICH guidelines. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen) to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.